Prohibitin antibody (AA 99-129)

Catalog No. ABIN543509

Product Details anti-Prohibitin Antibody

Target: Prohibitin (PHB)

Binding Specificity: AA 99-129

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PHB.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 99-129 at N-terminus of human PHB.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Prohibitin antibody (ABIN543509)

Ross, Nagy, Kirken: "The PHB1/2 phosphocomplex is required for mitochondrial homeostasis and survival of human T cells." in: The Journal of biological chemistry, Vol. 283, Issue 8, pp. 4699-713, (2008) (PubMed).

Gregory-Bass, Olatinwo, Xu, Matthews, Stiles, Thomas, Liu, Tsang, Thompson: "Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 9, pp. 1923-30, (2008) (PubMed).

Target Details for Prohibitin

Target: Prohibitin (PHB)

Alternative Name: Prohibitin / PHB (PHB Products)

Synonyms: phb1 antibody, MGC75944 antibody, PHB antibody, Phb antibody, ACYPI000080 antibody, phb antibody, PHB1 antibody, Bap32 antibody, sr:nyz128 antibody, wu:fa18f07 antibody, wu:fb09f05 antibody, prohibitin1 antibody, xphb1 antibody, prohibitin antibody, prohibitin-2 antibody, prohibitin L homeolog antibody, PHB antibody, phb antibody, LOC484431 antibody, LOC5576054 antibody, Phb antibody, phb.L antibody

Gene ID: 5245

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling