MKNK1 antibody (N-Term)

Catalog No. ABIN543670

Product Details anti-MKNK1 Antibody

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of MKNK1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MKNK1.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-MKNK1 antibody (ABIN543670)

Cuesta, Xi, Schneider: "Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein." in: Journal of virology, Vol. 78, Issue 14, pp. 7707-16, (2004) (PubMed).

Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: "Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38649-57, (2004) (PubMed).

Knauf, Tschopp, Gram: "Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2." in: Molecular and cellular biology, Vol. 21, Issue 16, pp. 5500-11, (2001) (PubMed).

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MKNK1 (MKNK1 Products)

Synonyms: MNK1 antibody, MKNK1 antibody, zgc:171912 antibody, 2410048M24Rik antibody, Mnk1 antibody, MAPK signal-integrating kinase 1 antibody, mknk1 antibody, mnk1 antibody, MAP kinase interacting serine/threonine kinase 1 antibody, MAP kinase-interacting serine/threonine kinase 1 antibody, MAP kinase interacting serine/threonine kinase 1 S homeolog antibody, MKNK1 antibody, mknk1 antibody, Mknk1 antibody, mknk1.S antibody

Gene ID: 8569

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor