LINGO1 antibody (N-Term)

Catalog No. ABIN543819

Product Details anti-LINGO1 Antibody

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of LINGO1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LINGO1.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-LINGO1 antibody (ABIN543819)

Satoh, Tabunoki, Yamamura, Arima, Konno: "TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions." in: Neuropathology and applied neurobiology, Vol. 33, Issue 1, pp. 99-107, (2007) (PubMed).

Inoue, Lin, Lee, Shao, Mendes, Snodgrass-Belt, Sweigard, Engber, Pepinsky, Yang, Beal, Mi, Isacson: "Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 36, pp. 14430-5, (2007) (PubMed).

Mosyak, Wood, Dwyer, Buddha, Johnson, Aulabaugh, Zhong, Presman, Benard, Kelleher, Wilhelm, Stahl, Kriz, Gao, Cao, Ling, Pangalos, Walsh, Somers: "The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition." in: The Journal of biological chemistry, Vol. 281, Issue 47, pp. 36378-90, (2006) (PubMed).

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO1 (LINGO1 Products)

Synonyms: lern1 antibody, lrrn6a antibody, unq201 antibody, DKFZp459P0736 antibody, LERN1 antibody, LRRN6A antibody, UNQ201 antibody, 4930471K13Rik antibody, AV148400 antibody, LINGO-1 antibody, Lrrn6a antibody, leucine rich repeat and Ig domain containing 1 antibody, LINGO1 antibody, lingo1 antibody, Lingo1 antibody

Gene ID: 84894