CDK4 antibody (AA 273-305)

Catalog No. ABIN543876

Product Details anti-CDK4 Antibody

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Binding Specificity: AA 273-305

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CDK4.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 273-305 at C-terminus of human CDK4.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CDK4 antibody (ABIN543876)

Gump, Stokoe, McCormick: "Phosphorylation of p16INK4A correlates with Cdk4 association." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 6619-22, (2003) (PubMed).

Masaki, Shiratori, Rengifo, Igarashi, Yamagata, Kurokohchi, Uchida, Miyauchi, Yoshiji, Watanabe, Omata, Kuriyama: "Cyclins and cyclin-dependent kinases: comparative study of hepatocellular carcinoma versus cirrhosis." in: Hepatology (Baltimore, Md.), Vol. 37, Issue 3, pp. 534-43, (2003) (PubMed).

Mori, Yang, Kawamata, Miller, Mizoguchi, Koeffler: "Absence of R24C mutation of the CDK4 gene in leukemias and solid tumors." in: International journal of hematology, Vol. 77, Issue 3, pp. 259-62, (2003) (PubMed).

Target Details for CDK4

Target: CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

Alternative Name: CDK4 (CDK4 Products)

Synonyms: zgc:153726 antibody, CMM3 antibody, PSK-J3 antibody, Crk3 antibody, 8-6 antibody, CDK4 antibody, CDK4/6 antibody, CG5072 antibody, Cdk4/6 antibody, DmCdk4 antibody, Dmel\\CG5072 antibody, Pk53C antibody, Pk?7 antibody, cdk antibody, cdk4 antibody, cdk4/6 antibody, dCdk4 antibody, l(2)05428 antibody, l(2)0671 antibody, l(2)k06503 antibody, l(2)s4639 antibody, l(2)sh0671 antibody, xcdk4 antibody, cyclin-dependent kinase 4 antibody, cyclin dependent kinase 4 antibody, Cyclin-dependent kinase 4 antibody, cyclin-dependent kinase 4 L homeolog antibody, cdk4 antibody, CDK4 antibody, Cdk4 antibody, cdk4.L antibody

Gene ID: 1019

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size