PTPN7 antibody (Ser44)

Catalog No. ABIN543957

Product Details anti-PTPN7 Antibody

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Binding Specificity: Ser44

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PTPN7.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S44 of human PTPN7.

Application Details

Application Notes: Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PTPN7 antibody (ABIN543957)

Eswaran, von Kries, Marsden, Longman, Debreczeni, Ugochukwu, Turnbull, Lee, Knapp, Barr: "Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases." in: The Biochemical journal, Vol. 395, Issue 3, pp. 483-91, (2006) (PubMed).

Mustelin, Tautz, Page: "Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site." in: Journal of molecular biology, Vol. 354, Issue 1, pp. 150-63, (2005) (PubMed).

Pettiford, Herbst: "The protein tyrosine phosphatase HePTP regulates nuclear translocation of ERK2 and can modulate megakaryocytic differentiation of K562 cells." in: Leukemia, Vol. 17, Issue 2, pp. 366-78, (2003) (PubMed).

Target Details for PTPN7

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Alternative Name: PTPN7 / HEPTP (PTPN7 Products)

Synonyms: BPTP-4 antibody, HEPTP antibody, LC-PTP antibody, LPTP antibody, PTPNI antibody, C920001D21Rik antibody, Heptp antibody, Lcptp antibody, protein tyrosine phosphatase, non-receptor type 7 antibody, PTPN7 antibody, Ptpn7 antibody

Gene ID: 5778