FGFR2
Reactivity: Human, Mouse, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Flow Cytometry (1:25) Immunofluorescence (1:25) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide).
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Goriely, McVean, Röjmyr, Ingemarsson, Wilkie: "Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line." in: Science (New York, N.Y.), Vol. 301, Issue 5633, pp. 643-6, (2003) (PubMed).
Fomenkov, Huang, Topaloglu, Brechman, Osada, Fomenkova, Yuriditsky, Trink, Sidransky, Ratovitski: "P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23906-14, (2003) (PubMed).
Freeman, Gangula, Welm, Ozen, Foster, Rosen, Ittmann, Greenberg, Spencer et al.: "Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase ..." in: Cancer research, Vol. 63, Issue 19, pp. 6237-43, (2003) (PubMed).