Ret Proto-Oncogene antibody (N-Term)

Catalog No. ABIN544339

Product Details anti-Ret Proto-Oncogene Antibody

Target: Ret Proto-Oncogene (RET)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ret Proto-Oncogene antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of RET.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human RET.

Application Details

Application Notes: Flow Cytometry (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Ret Proto-Oncogene antibody (ABIN544339)

DAlessio, Califano, Incoronato, Santelli, Florio, Schettini, Carlomagno, Cerchia, de Franciscis: "The tyrosine phosphatase Shp-2 mediates intracellular signaling initiated by Ret mutants." in: Endocrinology, Vol. 144, Issue 10, pp. 4298-305, (2003) (PubMed).

McWhinney, Boru, Binkley, Peczkowska, Januszewicz, Neumann, Eng: "Intronic single nucleotide polymorphisms in the RET protooncogene are associated with a subset of apparently sporadic pheochromocytoma and may modulate age of onset." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 10, pp. 4911-6, (2003) (PubMed).

Da Silva, Maciel, Da Silva, Toledo, De Carvalho, Cerutti: "A novel germ-line point mutation in RET exon 8 (Gly(533)Cys) in a large kindred with familial medullary thyroid carcinoma." in: The Journal of clinical endocrinology and metabolism, Vol. 88, Issue 11, pp. 5438-43, (2003) (PubMed).

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: RET (RET Products)

Synonyms: c-ret antibody, cret antibody, etID315074.13 antibody, ret1 antibody, wu:fd13h01 antibody, X-ret antibody, ret-A antibody, xret antibody, RET antibody, MTC1 antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, RET9 antibody, c-Ret antibody, ret proto-oncogene receptor tyrosine kinase antibody, ret proto-oncogene S homeolog antibody, ret proto-oncogene antibody, ret antibody, ret.S antibody, RET antibody, Ret antibody

Gene ID: 5979

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation