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LYN antibody (N-Term)

LYN Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN544389
  • Target See all LYN Antibodies
    LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))
    Binding Specificity
    • 22
    • 18
    • 16
    • 13
    • 9
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 136
    • 98
    • 74
    • 21
    • 16
    • 15
    • 15
    • 14
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Mouse
    Host
    • 134
    • 13
    • 1
    • 1
    Rabbit
    Clonality
    • 130
    • 20
    Polyclonal
    Conjugate
    • 79
    • 11
    • 11
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This LYN antibody is un-conjugated
    Application
    • 125
    • 63
    • 46
    • 25
    • 24
    • 21
    • 17
    • 14
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purpose
    Rabbit polyclonal antibody raised against synthetic peptide of LYN.
    Cross-Reactivity
    Human, Mouse
    Immunogen
    A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human LYN.
    Top Product
    Discover our top product LYN Primary Antibody
  • Application Notes
    Flow Cytometry (1:10-50)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In PBS (0.09 % sodium azide)
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Baran, Tridandapani, Helgason, Humphries, Krystal, Marsh: "The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38628-36, (2003) (PubMed).

    Donato, Wu, Stapley, Gallick, Lin, Arlinghaus, Talpaz: "BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571." in: Blood, Vol. 101, Issue 2, pp. 690-8, (2003) (PubMed).

    Santini, Scappini, Grossi, Gozzini, Bonsi, Pagliai, Rossi Ferrini, Bagnara: "Lyn kinase is activated following thrombopoietin stimulation of the megakaryocytic cell line B1647." in: Haematologica, Vol. 87, Issue 12, pp. 1242-7, (2002) (PubMed).

  • Target
    LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))
    Alternative Name
    LYN (LYN Products)
    Synonyms
    JTK8 antibody, p53Lyn antibody, p56Lyn antibody, lyn antibody, LYN antibody, AA407514 antibody, Hck-2 antibody, jtk8 antibody, lyn-A antibody, CH73-38P6.3 antibody, zgc:92124 antibody, LYN proto-oncogene, Src family tyrosine kinase antibody, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog antibody, tyrosine-protein kinase Lyn antibody, LYN proto-oncogene, Src family tyrosine kinase L homeolog antibody, LYN antibody, lyn antibody, Lyn antibody, LOC100593961 antibody, lyn.L antibody
    Gene ID
    4067
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling
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