GTPase NRas antibody (N-Term)

Catalog No. ABIN544419

Product Details anti-GTPase NRas Antibody

Target: GTPase NRas (NRAS)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTPase NRas antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of NRAS.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NRAS.

Application Details

Application Notes: Flow Cytometry (1:10-50)
Immunofluorescence (1:10-50)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-GTPase NRas antibody (ABIN544419)

Banerji, Affolter, Judson, Marais, Workman: "BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors." in: Molecular cancer therapeutics, Vol. 7, Issue 4, pp. 737-9, (2008) (PubMed).

Smalley, Contractor, Nguyen, Xiao, Edwards, Muthusamy, King, Flaherty, Bosenberg, Herlyn, Nathanson: "Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression." in: Cancer research, Vol. 68, Issue 14, pp. 5743-52, (2008) (PubMed).

Target Details for GTPase NRas

Target: GTPase NRas (NRAS)

Alternative Name: NRAS (NRAS Products)

Synonyms: NRAS antibody, AV095280 antibody, N-ras antibody, ALPS4 antibody, NRAS1 antibody, NS6 antibody, N-RAS antibody, fj99a10 antibody, wu:fj99a10 antibody, zgc:100761 antibody, zras-b1 antibody, H-RAS antibody, HRAS antibody, GTPase NRas antibody, neuroblastoma RAS viral (v-ras) oncogene homolog L homeolog antibody, NRAS proto-oncogene, GTPase antibody, neuroblastoma ras oncogene antibody, neuroblastoma RAS viral oncogene homolog antibody, Tsp_01117 antibody, nras.L antibody, Nras antibody, NRAS antibody, nras antibody

Gene ID: 4893

Pathways: p53 Signaling, MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling