SIGLEC7 antibody (N-Term)

Catalog No. ABIN544596

Product Details anti-SIGLEC7 Antibody

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIGLEC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of SIGLEC7.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SIGLEC7.

Application Details

Application Notes: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-SIGLEC7 antibody (ABIN544596)

Alphey, Attrill, Crocker, van Aalten: "High resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec family." in: The Journal of biological chemistry, Vol. 278, Issue 5, pp. 3372-7, (2003) (PubMed).

Nicoll, Avril, Lock, Furukawa, Bovin, Crocker: "Ganglioside GD3 expression on target cells can modulate NK cell cytotoxicity via siglec-7-dependent and -independent mechanisms." in: European journal of immunology, Vol. 33, Issue 6, pp. 1642-8, (2003) (PubMed).

Angata, Varki: "Siglec-7: a sialic acid-binding lectin of the immunoglobulin superfamily." in: Glycobiology, Vol. 10, Issue 4, pp. 431-8, (2000) (PubMed).

Target Details for SIGLEC7

Target: SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))

Alternative Name: CD328 / SIGLEC7 (SIGLEC7 Products)

Synonyms: SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody

Gene ID: 27036