Endoribonuclease Dcr-1 (Dcr-1) (Internal Region) antibody

Catalog No. ABIN544750

Product Details

Target: Endoribonuclease Dcr-1 (Dcr-1)

Binding Specificity: Internal Region

Reactivity: Nematode, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of dcr-1.

Cross-Reactivity: Human, Nematode

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of C.elegans dcr-1.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References

Duchaine, Wohlschlegel, Kennedy, Bei, Conte, Pang, Brownell, Harding, Mitani, Ruvkun, Yates, Mello: "Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways." in: Cell, Vol. 124, Issue 2, pp. 343-54, (2006) (PubMed).

Denli, Tops, Plasterk, Ketting, Hannon: "Processing of primary microRNAs by the Microprocessor complex." in: Nature, Vol. 432, Issue 7014, pp. 231-5, (2004) (PubMed).

Tabara, Yigit, Siomi, Mello: "The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans." in: Cell, Vol. 109, Issue 7, pp. 861-71, (2002) (PubMed).

Target Details

Target: Endoribonuclease Dcr-1 (Dcr-1)

Alternative Name: dcr-1 (Dcr-1 Products)

Synonyms: Endoribonuclease dcr-1 antibody, dcr-1 antibody

Gene ID: 176138