MAPT antibody (C-Term)

Catalog No. ABIN544823

Product Details anti-MAPT Antibody

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of MAPT.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MAPT.

Application Details

Application Notes: Immunofluorescence (1:10-50)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:25)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-MAPT antibody (ABIN544823)

Gamblin, Chen, Zambrano, Abraha, Lagalwar, Guillozet, Lu, Fu, Garcia-Sierra, LaPointe, Miller, Berry, Binder, Cryns: "Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 17, pp. 10032-7, (2003) (PubMed).

Horiguchi, Uryu, Giasson, Ischiropoulos, LightFoot, Bellmann, Richter-Landsberg, Lee, Trojanowski: "Nitration of tau protein is linked to neurodegeneration in tauopathies." in: The American journal of pathology, Vol. 163, Issue 3, pp. 1021-31, (2003) (PubMed).

Yoshiyama, Zhang, Bruce, Trojanowski, Lee: "Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 33, pp. 10662-71, (2003) (PubMed).

Target Details for MAPT

Target: MAPT (Microtubule-Associated Protein tau (MAPT))

Alternative Name: MAPT / TAU (MAPT Products)

Synonyms: DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, AI413597 antibody, AW045860 antibody, Mtapt antibody, Tau antibody, RNPTAU antibody, pTau antibody, tau antibody, xtp antibody, MAPT antibody, PHF-tau antibody, slc6a6 antibody, taut antibody, wu:fc26e12 antibody, microtubule associated protein tau antibody, microtubule-associated protein tau antibody, microtubule associated protein tau S homeolog antibody, Microtubule-associated protein tau antibody, solute carrier family 6 (neurotransmitter transporter), member 6b antibody, MAPT antibody, Mapt antibody, mapt.S antibody, LOC5580230 antibody, CpipJ_CPIJ013260 antibody, tau antibody, slc6a6b antibody

Gene ID: 4137

Pathways: MAPK Signaling, Microtubule Dynamics, M Phase, Regulation of Cell Size