PPP2CA antibody (N-Term)

Catalog No. ABIN545076

Product Details anti-PPP2CA Antibody

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2CA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of PPP2CA.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PPP2CA.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PPP2CA antibody (ABIN545076)

Gergs, Boknik, Buchwalow, Fabritz, Matus, Justus, Hanske, Schmitz, Neumann: "Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40827-34, (2004) (PubMed).

Prickett, Brautigan: "Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 38912-20, (2004) (PubMed).

Scott, Gu, Crump, Thomas, Wan, Xiang, Thomas: "The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic." in: The EMBO journal, Vol. 22, Issue 23, pp. 6234-44, (2003) (PubMed).

Target Details for PPP2CA

Target: PPP2CA (Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

Alternative Name: PPP2CA (PPP2CA Products)

Synonyms: PP2Ac antibody, PP2CA antibody, PP2Calpha antibody, RP-C antibody, PP2A antibody, R75353 antibody, Pp2a1 antibody, pp2ac antibody, zgc:110641 antibody, protein phosphatase 2 catalytic subunit alpha antibody, protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform antibody, protein phosphatase 2, catalytic subunit, alpha isozyme antibody, protein phosphatase 2 catalytic subunit alpha L homeolog antibody, protein phosphatase 2, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform antibody, PPP2CA antibody, Ppp2ca antibody, ppp2ca.L antibody, ppp2cb antibody, LOC471633 antibody, ppp2ca antibody

Gene ID: 5515

Pathways: PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C, Toll-Like Receptors Cascades