MYB antibody

Catalog No. ABIN545264

Product Details anti-MYB Antibody

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of MYB.

Sequence: PLLKKIKQEV ESPTCA

Specificity: This antibody recognize synthetic peptide (PLLKKIKQEVESPTCA) containing a predicted sumoylation site of human MYB.

Cross-Reactivity: Human, Mouse

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to human MYB.

Application Details

Application Notes: ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-MYB antibody (ABIN545264)

Luchetti, Paroncini, Majlingovà, Frampton, Mucenski, Baroni, Sambo, Golay, Introna, Gabrielli: "Characterization of the c-Myb-responsive region and regulation of the human type I collagen alpha 2 chain gene by c-Myb." in: The Journal of biological chemistry, Vol. 278, Issue 3, pp. 1533-41, (2003) (PubMed).

Dahle, Andersen, Nordgård, Matre, Del Sal, Gabrielsen: "Transactivation properties of c-Myb are critically dependent on two SUMO-1 acceptor sites that are conjugated in a PIASy enhanced manner." in: European journal of biochemistry / FEBS, Vol. 270, Issue 6, pp. 1338-48, (2003) (PubMed).

Chen, Kremer, Bender: "A Myb dependent pathway maintains Friend murine erythroleukemia cells in an immature and proliferating state." in: Oncogene, Vol. 21, Issue 12, pp. 1859-69, (2002) (PubMed).

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB (MYB Products)

Synonyms: Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody

Gene ID: 4602

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process