PKC iota antibody (Protein Kinase C, iota)

Details for Product anti-PRKCI Antibody No. ABIN545464
Target
Reactivity
Human
49
24
17
6
6
2
2
2
2
2
1
1
1
Host
Rabbit
43
6
Clonality
Polyclonal
Conjugate
This PKC iota antibody is un-conjugated
6
5
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
35
24
22
12
3
2
2
1
1
Options
Purpose Rabbit polyclonal antibody raised against synthetic peptide of PRKCI.
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human PRKCI.
Cross-Reactivity Mouse (Murine)
Target
Alternative Name PRKCI (PRKCI Antibody Abstract)
Pathways Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
Application Notes ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
Restrictions For Research Use only
Buffer In PBS (0.09 % sodium azide)
Storage 4 °C,-20 °C
Storage Comment Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Images
Image no. 1 for anti-Protein Kinase C, iota (PRKCI) antibody (ABIN545464) Western blot analysis of PRKCI polyclonal antibody in mouse lung lysate . PRKCI (arr...
Image no. 2 for anti-Protein Kinase C, iota (PRKCI) antibody (ABIN545464) Western blot analysis of PRKCI (arrow) using rabbit PRKCI polyclonal antibody . 293 c...
Image no. 3 for anti-Protein Kinase C, iota (PRKCI) antibody (ABIN545464) Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted wi...
Product cited in: Zhang, Anastasiadis, Liu, Thompson, Fields: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." in: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, 2004 (PubMed).

Roehrl, Hyberts, Sun, Fields, Wagner: "Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS." in: Journal of biomolecular NMR, Vol. 26, Issue 4, pp. 373-4, 2003 (PubMed).

Tisdale: "Rab2 interacts directly with atypical protein kinase C (aPKC) iota/lambda and inhibits aPKCiota/lambda-dependent glyceraldehyde-3-phosphate dehydrogenase phosphorylation." in: The Journal of biological chemistry, Vol. 278, Issue 52, pp. 52524-30, 2003 (PubMed).