Neuregulin 1 antibody (Internal Region)

Catalog No. ABIN545729

Product Details anti-Neuregulin 1 Antibody

Target: Neuregulin 1 (NRG1)

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of NRG1.

Cross-Reactivity: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to internal region of human NRG1.

Application Details

Application Notes: Flow cytometry (1:10-50)
Immunohistochemistry (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Neuregulin 1 antibody (ABIN545729)

Ritch, Carroll, Sontheimer: "Neuregulin-1 enhances motility and migration of human astrocytic glioma cells." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20971-8, (2003) (PubMed).

Adélaïde, Huang, Murati, Alsop, Orsetti, Mozziconacci, Popovici, Ginestier, Letessier, Basset, Courtay-Cahen, Jacquemier, Theillet, Birnbaum, Edwards, Chaffanet: "A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene." in: Genes, chromosomes & cancer, Vol. 37, Issue 4, pp. 333-45, (2003) (PubMed).

Stove, Stove, Derycke, Van Marck, Mareel, Bracke: "The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation." in: The Journal of investigative dermatology, Vol. 121, Issue 4, pp. 802-12, (2003) (PubMed).

Target Details for Neuregulin 1

Target: Neuregulin 1 (NRG1)

Alternative Name: Neuregulin 1 (NRG1 Products)

Synonyms: 6030402G23Rik antibody, ARIA antibody, D230005F13Rik antibody, GGF antibody, GGFII antibody, HRG antibody, HRGalpha antibody, Hgl antibody, NDF antibody, SMDF antibody, GGF2 antibody, HGL antibody, HRG1 antibody, HRGA antibody, MST131 antibody, NRG-1 antibody, heregulin antibody, nrg1-A antibody, pro-neuregulin-1 antibody, NRG1 antibody, wu:fm70e01 antibody, DKFZp459A1838 antibody, neuregulin 1 antibody, histidine rich glycoprotein antibody, neuregulin 1 L homeolog antibody, Nrg1 antibody, NRG1 antibody, HRG antibody, nrg1.L antibody, nrg1 antibody

Gene ID: 3084

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation