Presenilin 1 antibody (C-Term)
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- Target See all Presenilin 1 (PSEN1) Antibodies
- Presenilin 1 (PSEN1)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Presenilin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit polyclonal antibody raised against synthetic peptide of PSEN1.
- Cross-Reactivity
- Human, Mouse
- Immunogen
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PSEN1.
- Top Product
- Discover our top product PSEN1 Primary Antibody
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- Application Notes
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ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In PBS (0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease." in: Neurobiology of aging, Vol. 24, Issue 5, pp. 655-62, (2003) (PubMed).
: "Regulated hyperaccumulation of presenilin-1 and the "gamma-secretase" complex. Evidence for differential intramembranous processing of transmembrane subatrates." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33992-4002, (2003) (PubMed).
: "A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations." in: Cell, Vol. 114, Issue 5, pp. 635-45, (2003) (PubMed).
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Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease." in: Neurobiology of aging, Vol. 24, Issue 5, pp. 655-62, (2003) (PubMed).
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- Target
- Presenilin 1 (PSEN1)
- Alternative Name
- Presenilin-1 (PSEN1 Products)
- Synonyms
- pre1 antibody, psen antibody, zfPS1 antibody, zf-PS1 antibody, ad3 antibody, fad antibody, ps1 antibody, s182 antibody, X-PS-beta antibody, X-PS-alpha antibody, AD3 antibody, FAD antibody, PS-1 antibody, PS1 antibody, S182 antibody, Ad3h antibody, presenilin 1 antibody, presenilin 1 L homeolog antibody, psen1 antibody, PSEN1 antibody, Psen1 antibody, psen1.L antibody
- Gene ID
- 5663
- Pathways
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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