TRIM5 antibody

Catalog No. ABIN547064

Product Details anti-TRIM5 Antibody

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TRIM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Goat polyclonal antibody raised against synthetic peptide of TRIM5.

Sequence: ASGILVNVKE EVTC

Specificity: This antibody is expected to recognize all three human isoforms of this protein.

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to human TRIM5.

Application Details

Application Notes: ELISA (1:16000)
Western Blot (1-3 μg/mL)
Immunohistochemistry (1 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In Tris saline, pH 7.3 (0.5 % BSA, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-TRIM5 antibody (ABIN547064)

Yap, Lindemann, Stanke, Reh, Westphal, Hanenberg, Ohkura, Stoye: "Restriction of foamy viruses by primate Trim5alpha." in: Journal of virology, Vol. 82, Issue 11, pp. 5429-39, (2008) (PubMed).

Yap, Mortuza, Taylor, Stoye: "The design of artificial retroviral restriction factors." in: Virology, Vol. 365, Issue 2, pp. 302-14, (2007) (PubMed).

Ohkura, Yap, Sheldon, Stoye: "All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restriction." in: Journal of virology, Vol. 80, Issue 17, pp. 8554-65, (2006) (PubMed).

Target Details for TRIM5

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Alternative Name: TRIM5 / RNF88 (TRIM5 Products)

Synonyms: TRIM5 antibody, RNF88 antibody, TRIM5alpha antibody, EG667823 antibody, Gm8833 antibody, RGD1304579 antibody, tripartite motif containing 5 antibody, tripartite motif-containing 5 antibody, TRIM5 antibody, Trim5 antibody

Gene ID: 85363

Pathways: Activation of Innate immune Response