Retinoic Acid Receptor alpha antibody

Catalog No. ABIN547411

Product Details anti-Retinoic Acid Receptor alpha Antibody

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This Retinoic Acid Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Goat polyclonal antibody raised against synthetic peptide of RARA.

Sequence: C-SPSLSPSSHR SSPATQSP

Specificity: NP_000955.1 (isfa) and NP_001028775.1(alpha) represent identical proteins. This antibody is expected to recognize all three reported isoforms (NP_000955.1, NP_001019980.1, NP_001028775.1). Please note the epitope is from the mouse/rat sequence. Human sequence is SPSLSPSSNRSSPATHSP and thus highly similar.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to human RARA.

Application Details

Application Notes: ELISA (1:8000)
Western blot (1-3 μg/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 μg/mL)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: In Tris saline, pH 7.3 (0.5 % BSA, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Retinoic Acid Receptor alpha antibody (ABIN547411)

Farias, Ong, Ghyselinck, Nakajo, Kuppumbatti, Mira y Lopez: "Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity." in: Journal of the National Cancer Institute, Vol. 97, Issue 1, pp. 21-9, (2005) (PubMed).

Target Details for Retinoic Acid Receptor alpha

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Alternative Name: RAR-alpha / RARA (RARA Products)

Synonyms: NR1B1 antibody, RAR antibody, Nr1b1 antibody, RARalpha1 antibody, rar-alpha antibody, etID309833.12 antibody, rara antibody, rara2a antibody, zRAR antibody, zRAR-alpha antibody, zgc:109797 antibody, nr1b1 antibody, RAR-ALPHA1 antibody, HS-RARa antibody, fj66e06 antibody, rara2b antibody, wu:fj66e06 antibody, retinoic acid receptor alpha antibody, retinoic acid receptor, alpha antibody, retinoic acid receptor, alpha a antibody, retinoic acid receptor alpha L homeolog antibody, retinoic acid receptor, alpha b antibody, RARA antibody, Rara antibody, LOC100136372 antibody, raraa antibody, rara.L antibody, rara antibody, rarab antibody

Gene ID: 5914

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins