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ABL1 antibody (pTyr245)
ABL1
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ABL1 Antibody
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Target
See all ABL1 Antibodies
ABL1
(C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
Binding Specificity
All epitopes for ABL1 antibodies
pTyr245
Reactivity
All reactivities for ABL1 antibodies
Human, Mouse, Rat
Host
All hosts for ABL1 antibodies
Rabbit
Clonality
All clonalities for ABL1 antibodies
Polyclonal
Conjugate
All conjugates for ABL1 antibodies
This ABL1 antibody is un-conjugated
Application
All applications for ABL1 antibodies
Western Blotting (WB), ELISA
Purpose
Rabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1.
Specificity
This peptide sequence has high homology to the conserved site in rat and mouse c-Abl, as well as in viral Abl and BCR-Abl fusion protein.
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Antibody Reactive Against Synthetic Peptide.
Immunogen
Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y245 of human ABL1.
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Discover our top product ABL1 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA (1:2000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
References for anti-ABL1 antibody (ABIN548465)
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Pluk, Dorey, Superti-Furga : "Autoinhibition of c-Abl. " in: Cell , Vol. 108 , Issue 2 , pp. 247-59 , (2002 ) (PubMed ).
Brasher, Van Etten : "c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines. " in: The Journal of biological chemistry , Vol. 275 , Issue 45 , pp. 35631-7 , (2000 ) (PubMed ).
Target Details for ABL1
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Target
ABL1
(C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
Alternative Name
ABL1 (ABL1 Products )
Synonyms
ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody
Gene ID
25
Pathways
Apoptosis , Regulation of Muscle Cell Differentiation , Platelet-derived growth Factor Receptor Signaling , Lipid Metabolism
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