This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Block, Eid, Griendling, Lee, Wittrant, Gorin: "Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24061-76, (2008) (PubMed).
Scheid, Parsons, Woodgett: "Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation." in: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2347-63, (2005) (PubMed).
Taniyama, Weber, Rocic, Hilenski, Akers, Park, Hemmings, Alexander, Griendling: "Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions." in: Molecular and cellular biology, Vol. 23, Issue 22, pp. 8019-29, (2003) (PubMed).
Target
PDPK1
(3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))