Paxillin antibody (pSer83)

Catalog No. ABIN548479

Product Details anti-Paxillin Antibody

Target: Paxillin (PXN)

Binding Specificity: pSer83

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paxillin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Pxn.

Specificity: This sequence is highly conserved in rat paxillin and is also found in all isoforms (a, b, g) of paxillin.

Cross-Reactivity: Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S83 of mouse Pxn.

Application Details

Application Notes: ELISA (1:2000)
Immunocytochemistry (1:10)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Paxillin antibody (ABIN548479)

Huang, Borchers, Schaller, Jacobson: "Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells." in: The Journal of cell biology, Vol. 164, Issue 4, pp. 593-602, (2004) (PubMed).

Ishibe, Joly, Liu, Cantley: "Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis." in: Molecular cell, Vol. 16, Issue 2, pp. 257-67, (2004) (PubMed).

Target Details for Paxillin

Target: Paxillin (PXN)

Alternative Name: Paxillin / PXN (PXN Products)

Synonyms: AW108311 antibody, AW123232 antibody, Pax antibody, CG18061 antibody, CG18576 antibody, CG31794 antibody, CT40481 antibody, CT42454 antibody, DPaxillin antibody, DPxn antibody, DPxn37 antibody, Dmel\\CG31794 antibody, Dpax antibody, DpaxA antibody, PDLP antibody, dPax antibody, pax antibody, wu:fw71f12 antibody, PXN antibody, LOC100220858 antibody, paxillin antibody, Paxillin antibody, paxillin S homeolog antibody, paxillin a antibody, PXN antibody, Pxn antibody, Pax antibody, pxn.S antibody, pxna antibody, LOC696336 antibody, pxn antibody

Gene ID: 19303

Pathways: MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling