ELISA (1:1000) Dot Blot (1:500) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Dong, Patino-Lopez, Candotti, Shaw: "Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30303-10, (2007) (PubMed).
Gibson, Hedgcock, Aufiero, Wilson, Hafner, Tsokos, Wong: "Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3831-40, (2007) (PubMed).
Golks, Tran, Goetschy, Guerini: "Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation." in: The EMBO journal, Vol. 26, Issue 20, pp. 4368-79, (2007) (PubMed).
Target
NFAT1
(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))