Insulin Receptor antibody (pTyr1185)
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- Target See all Insulin Receptor (INSR) Antibodies
- Insulin Receptor (INSR)
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Binding Specificity
- pTyr1185
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Insulin Receptor antibody is un-conjugated
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Application
- ELISA, Dot Blot (DB)
- Purpose
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of INSR.
- Cross-Reactivity
- Human
- Immunogen
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1185 of human INSR.
- Top Product
- Discover our top product INSR Primary Antibody
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- Application Notes
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ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In PBS (0.09 % sodium azide)
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6441-6, (2005) (PubMed).
: "AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells." in: Biochemical and biophysical research communications, Vol. 328, Issue 2, pp. 449-54, (2005) (PubMed).
: "Placental insulin and insulin-like growth factor I receptors in normal and preeclamptic pregnancies." in: Clinical biochemistry, Vol. 38, Issue 3, pp. 243-7, (2005) (PubMed).
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Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6441-6, (2005) (PubMed).
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- Target
- Insulin Receptor (INSR)
- Alternative Name
- CD220 / INSR (INSR Products)
- Synonyms
- CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
- Gene ID
- 3643
- Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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