IFNAR1 antibody (pSer535, pSer539)

Catalog No. ABIN550131

Product Details anti-IFNAR1 Antibody

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Binding Specificity: pSer535, pSer539

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNAR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of IFNAR1.

Cross-Reactivity: Cow, Dog, Human, Mouse, Primate, Rat, Sheep

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S535/S539 of human IFNAR1.

Application Details

Application Notes: Immunohistochemistry (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 100 μg/mL BSA).

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C for short term storage is acceptable as aliquots may be taken without freeze/thaw due to the presence of 50% glycerol. For long term storage, store at -80°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-IFNAR1 antibody (ABIN550131)

Kumar, Tang, Ravindranath, Clark, Croze, Fuchs: "SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor." in: The EMBO journal, Vol. 22, Issue 20, pp. 5480-90, (2003) (PubMed).

Kirkwood: "Cancer immunotherapy: the interferon-alpha experience." in: Seminars in oncology, Vol. 29, Issue 3 Suppl 7, pp. 18-26, (2002) (PubMed).

Biron: "Interferons alpha and beta as immune regulators--a new look." in: Immunity, Vol. 14, Issue 6, pp. 661-4, (2001) (PubMed).

Target Details for IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Alternative Name: IFNAR1 (IFNAR1 Products)

Synonyms: ifnar1 antibody, IFNAR1 antibody, CD118 antibody, Ifar antibody, Ifnar antibody, Ifrc antibody, Infar antibody, AVP antibody, IFN-alpha-REC antibody, IFNAR antibody, IFNBR antibody, IFRC antibody, IFN-R-1 antibody, interferon alpha and beta receptor subunit 1 antibody, interferon-alpha/beta receptor alpha chain-like antibody, interferon (alpha and beta) receptor 1 antibody, interferon alpha/beta receptor 1 antibody, IFNAR1 antibody, ifnar1 antibody, Ifnar1 antibody, LOC609830 antibody

Gene ID: 3454

Pathways: JAK-STAT Signaling, Hepatitis C