Metabotropic Glutamate Receptor 1 antibody (C-Term)

Catalog No. ABIN550140

Product Details anti-Metabotropic Glutamate Receptor 1 Antibody

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of Grm1/Grm5.

Specificity: Specific for the ~125KDa monomer and the ~250KDa dimers of mGluR5 and mGluR1.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide corresponding to C-terminus rat Grm1/Grm5.

Application Details

Application Notes: Immunohistochemistry (Frozen sections) (1:500)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 10 % BSA)

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Metabotropic Glutamate Receptor 1 antibody (ABIN550140)

Francesconi, Cammalleri, Sanna: "The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region." in: Brain research, Vol. 1022, Issue 1-2, pp. 12-8, (2004) (PubMed).

Bhattacharya, Babwah, Godin, Anborgh, Dale, Poulter, Ferguson: "Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 40, pp. 8752-61, (2004) (PubMed).

Blaabjerg, Fang, Zimmer, Baskys: "Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents." in: Experimental neurology, Vol. 183, Issue 2, pp. 573-80, (2003) (PubMed).

Target Details for Metabotropic Glutamate Receptor 1

Target: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Alternative Name: MGluR1a / GRM1a (GRM1 Products)

Synonyms: fj39d05 antibody, wu:fj39d05 antibody, si:ch211-51a19.1 antibody, Glura antibody, mGlutR antibody, GB18621 antibody, GPRC1A antibody, MGLU1 antibody, MGLUR1 antibody, SCAR13 antibody, 4930455H15Rik antibody, ENSMUSG00000075319 antibody, Gm10828 antibody, Gprc1a antibody, mGluR1 antibody, nmf373 antibody, rcw antibody, wobl antibody, glutamate metabotropic receptor 1 antibody, glutamate receptor, metabotropic 1a antibody, metabotropic glutamate receptor 1 antibody, glutamate receptor, metabotropic 1 antibody, GRM1 antibody, grm1a antibody, mGlutR1 antibody, Grm1 antibody

Gene ID: 24414, 24418