Tryptophan Hydroxylase 2 antibody (pSer19)

Catalog No. ABIN550168

Product Details anti-Tryptophan Hydroxylase 2 Antibody

Target: Tryptophan Hydroxylase 2 (TPH2)

Binding Specificity: pSer19

Reactivity: Mouse, Rat, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Tph2.

Cross-Reactivity: Cow, Mouse, Rat, Zebrafish (Danio rerio)

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S19 of rat Tph2.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 10 % BSA)

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-Tryptophan Hydroxylase 2 antibody (ABIN550168)

Kuhn, Sakowski, Geddes, Wilkerson, Haycock: "Phosphorylation and activation of tryptophan hydroxylase 2: identification of serine-19 as the substrate site for calcium, calmodulin-dependent protein kinase II." in: Journal of neurochemistry, Vol. 103, Issue 4, pp. 1567-73, (2007) (PubMed).

McKinney, Knappskog, Haavik: "Different properties of the central and peripheral forms of human tryptophan hydroxylase." in: Journal of neurochemistry, Vol. 92, Issue 2, pp. 311-20, (2005) (PubMed).

Martínez, Knappskog, Haavik: "A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis." in: Current medicinal chemistry, Vol. 8, Issue 9, pp. 1077-91, (2001) (PubMed).

Target Details for Tryptophan Hydroxylase 2

Target: Tryptophan Hydroxylase 2 (TPH2)

Alternative Name: Tryptophan 5-hydroxylase 2 (TPH2) (TPH2 Products)

Synonyms: ADHD7 antibody, NTPH antibody, Ntph antibody, tphR antibody, wu:fq15a04 antibody, AU043594 antibody, tryptophan hydroxylase 2 antibody, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) antibody, TPH2 antibody, Tph2 antibody, tph2 antibody

Gene ID: 317675