PAK2 antibody (pThr402)

Catalog No. ABIN550200

Product Details anti-PAK2 Antibody

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Binding Specificity: pThr402

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic phosphopeptide of Pak2.

Specificity: Specific for endogenous levels of the ~68 kDa PAK protein phosphorylated at Thr402. The immunolabeling is completely eliminated by treatment with lambda phosphatase.

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding phospho-T402 of rat Pak2.

Application Details

Application Notes: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 100 μg BSA per mL).

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-PAK2 antibody (ABIN550200)

Boda, Alberi, Nikonenko, Node-Langlois, Jourdain, Moosmayer, Parisi-Jourdain, Muller: "The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 48, pp. 10816-25, (2004) (PubMed).

Jakobi, McCarthy, Koeppel, Stringer: "Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38675-85, (2003) (PubMed).

Jakobi, Huang, Walter, Tuazon, Traugh: "Substrates enhance autophosphorylation and activation of p21-activated protein kinase gamma-PAK in the absence of activation loop phosphorylation." in: European journal of biochemistry / FEBS, Vol. 267, Issue 14, pp. 4414-21, (2000) (PubMed).

Target Details for PAK2

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Alternative Name: PAK2 (PAK2 Products)

Synonyms: PAK65 antibody, PAKgamma antibody, gamma-PAK antibody, 5330420P17Rik antibody, A130002K10Rik antibody, AI836325 antibody, D16Ertd269e antibody, PAK-2 antibody, mKIAA4182 antibody, pak2 antibody, cb422 antibody, kinase antibody, zgc:91798 antibody, wu:fb71h01 antibody, si:dz198m22.1 antibody, pak65 antibody, pakgamma antibody, PAKI antibody, Pak3 antibody, CH73-159L23.1 antibody, wu:fc52b03 antibody, zgc:113857 antibody, p21 (RAC1) activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2a antibody, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 2b antibody, PAK2 antibody, Pak2 antibody, pak2a antibody, pak2.S antibody, pak2b antibody

Gene ID: 29432

Pathways: MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha