NMDAR2A antibody (C-Term)

Catalog No. ABIN550222

Product Details anti-NMDAR2A Antibody

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Binding Specificity: C-Term

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMDAR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Rabbit polyclonal antibody raised against partial recombinant Grin2a.

Specificity: Recognizes human, mouse and rat forms of the NR2B subunits of NMDAR.

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: Recombinant protein corresponding to C-terminus rat Grin2a.

Application Details

Application Notes: Immunohistochemistry (Frozen sections) (1:1000-2000)
Immunoprecipitation (3 µL/200 μg lysate)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from 5 mM ammonium bicarbonate

Storage: -20 °C

Storage Comment: Store at -20°C on dry atmosphere.
After reconstitution with PBS, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.

References for anti-NMDAR2A antibody (ABIN550222)

Alvestad, Grosshans, Coultrap, Nakazawa, Yamamoto, Browning: "Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function." in: The Journal of biological chemistry, Vol. 278, Issue 13, pp. 11020-5, (2003) (PubMed).

Wenthold, Prybylowski, Standley, Sans, Petralia: "Trafficking of NMDA receptors." in: Annual review of pharmacology and toxicology, Vol. 43, pp. 335-58, (2003) (PubMed).

Carroll, Zukin: "NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity." in: Trends in neurosciences, Vol. 25, Issue 11, pp. 571-7, (2002) (PubMed).

Target Details for NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Alternative Name: NMDA Receptor 2A (GRIN2A Products)

Synonyms: NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody

Gene ID: 24409

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity