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SPIT2 antibody (Middle Region)
SPIT2
Reactivity: Human, Cow, Horse, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SPIT2 Antibody
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Target
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SPIT2
(Kunitz-Type Protease Inhibitor 2 (SPIT2))
Binding Specificity
Middle Region
Reactivity
Human, Cow, Horse, Pig
Host
All hosts for SPIT2 antibodies
Rabbit
Clonality
All clonalities for SPIT2 antibodies
Polyclonal
Conjugate
All conjugates for SPIT2 antibodies
This SPIT2 antibody is un-conjugated
Application
All applications for SPIT2 antibodies
Western Blotting (WB)
Sequence
ATGDLATSRN AADSSVPSAP RRQDSEDHSS DMFNYEEYCT ANAVTGPCRA
Predicted Reactivity
Cow: 86%, Horse: 79%, Human: 100%, Pig: 86%
Characteristics
This is a rabbit polyclonal antibody against SPIT2. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human SPIT2
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SPIT2
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Target
SPIT2
(Kunitz-Type Protease Inhibitor 2 (SPIT2))
Alternative Name
SPIT2 (SPIT2 Products )
Background
This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. Alias Symbols: SPINT2, HAI2, KOP, Protein Interaction Partner: TUBG1, APP, UBC, SUMO4, HGFAC, ITIH3, CTSB, ITIH2, Protein Size: 252
Gene ID
10653
NCBI Accession
NP_066925
UniProt
O43291
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