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SPIT2 antibody (Middle Region)

SPIT2 Reactivity: Human, Cow, Horse, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5514425
  • Target See all SPIT2 products
    SPIT2 (Kunitz-Type Protease Inhibitor 2 (SPIT2))
    Binding Specificity
    Middle Region
    Reactivity
    Human, Cow, Horse, Pig
    Host
    • 1
    Rabbit
    Clonality
    • 1
    Polyclonal
    Conjugate
    • 1
    This SPIT2 antibody is un-conjugated
    Application
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    ATGDLATSRN AADSSVPSAP RRQDSEDHSS DMFNYEEYCT ANAVTGPCRA
    Predicted Reactivity
    Cow: 86%, Horse: 79%, Human: 100%, Pig: 86%
    Characteristics
    This is a rabbit polyclonal antibody against SPIT2. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of Human SPIT2
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SPIT2 (Kunitz-Type Protease Inhibitor 2 (SPIT2))
    Alternative Name
    SPIT2 (SPIT2 Products)
    Background
    This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: SPINT2, HAI2, KOP,

    Protein Interaction Partner: TUBG1, APP, UBC, SUMO4, HGFAC, ITIH3, CTSB, ITIH2,

    Protein Size: 252
    Gene ID
    10653
    NCBI Accession
    NP_066925
    UniProt
    O43291
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