ATP6V1E1 antibody (N-Term)

Catalog No. ABIN5514460

Product Details anti-ATP6V1E1 Antibody

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1E1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IEQEANEKAE EIDAKAEEEF NIEKGRLVQT QRLKIMEYYE KKEKQIEQQK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against VATE1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human VATE1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATP6V1E1

Target: ATP6V1E1 (ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))

Alternative Name: VATE1 (ATP6V1E1 Products)

Synonyms: ATP6E antibody, ATP6E2 antibody, ATP6V1E antibody, P31 antibody, Vma4 antibody, 2410029D23Rik antibody, Atp6e antibody, Atp6e2 antibody, Atp6v1e antibody, D6Ertd385e antibody, E2 antibody, T22B4.130 antibody, T22B4_130 antibody, TUFF antibody, V-ATPase subunit E1 antibody, VACUOLAR H+-ATPASE SUBUNIT E ISOFORM 1 antibody, VHA-E1 antibody, emb2448 antibody, embryo defective 2448 antibody, vacuolar ATP synthase subunit E1 antibody, atp6e antibody, atp6v1e1 antibody, chunp6932 antibody, fj35f08 antibody, wu:fj35f08 antibody, ATPase H+ transporting V1 subunit E1 antibody, ATPase, H+ transporting, lysosomal V1 subunit E1 antibody, vacuolar ATP synthase subunit E1 antibody, ATPase, H+ transporting, lysosomal, V1 subunit E1b antibody, ATP6V1E1 antibody, Atp6v1e1 antibody, atp6v1e1 antibody, TUF antibody, atp6v1e1b antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.

Alias Symbols: ATP6V1E1, ATP6E, ATP6E2,

Protein Interaction Partner: UBC, SAMHD1, ATP6V1G1, ZNF827, SFXN1, TMEM43, SLC30A5, SUGP1, ZFR, ATP6V1H, ATP6V1D, TCIRG1, ALYREF, PPIF, SCAMP3, SCO2, ATP6V1F, VAPA, LAMTOR3, PICALM, YES1, XPNPEP1, TYMS, THY1, SSBP1, SRSF3, S100A10, YBX1, CD55, ABCC2, ATP6V0A1, ATP6V1C1, ATP6V1B2, ATP

Protein Size: 226

Gene ID: 529

NCBI Accession: NP_001687

UniProt: P36543

Pathways: Transition Metal Ion Homeostasis, Proton Transport