BFSP2 antibody (Middle Region)

Catalog No. ABIN5514575

Product Details anti-BFSP2 Antibody

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BFSP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CQQVGEAVLE NARLMLQTET IQAGADDFKE RYENEQPFRK AAEEEINSLY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BFSP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BFSP2

Target: BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))

Alternative Name: BFSP2 (BFSP2 Products)

Synonyms: CP47 antibody, CP49 antibody, CTRCT12 antibody, LIFL-L antibody, PHAKOSIN antibody, AI448593 antibody, CP49INS antibody, BFSP2 antibody, LOC100222605 antibody, Bfsp2 antibody, zgc:103750 antibody, beaded filament structural protein 2 antibody, beaded filament structural protein 2, phakinin antibody, BFSP2 antibody, Bfsp2 antibody, bfsp2 antibody

Background: More than 99 % of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.

Alias Symbols: CP47, CP49, LIFL-L, CTRCT12, PHAKOSIN

Protein Size: 415

Gene ID: 8419

NCBI Accession: NM_003571, NP_003562

UniProt: Q13515