CRTC3 antibody (Middle Region)

Catalog No. ABIN5514654

Product Details anti-CRTC3 Antibody

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PGRQFDGSAF GANYSSQPLD ESWPRQQPPW KDEKHPGFRL TSALNRTNSD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CRTC3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3 (CRTC3 Products)

Synonyms: torc3 antibody, MGC146372 antibody, 2610312F20Rik antibody, 6332415K15Rik antibody, AI429792 antibody, BC011210 antibody, TORC3 antibody, RGD1309666 antibody, TORC-3 antibody, CREB regulated transcription coactivator 3 antibody, CREB regulated transcription coactivator 3 L homeolog antibody, CRTC3 antibody, crtc3 antibody, Crtc3 antibody, crtc3.L antibody

Background: This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: TORC3, TORC-3

Protein Size: 619

Gene ID: 64784

NCBI Accession: NM_001042574, NP_001036039

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection