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DAD1 antibody (Middle Region)

DAD1 Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5514718
  • Target See all DAD1 Antibodies
    DAD1 (Defender Against Cell Death 1 (DAD1))
    Binding Specificity
    • 15
    • 8
    • 7
    • 5
    • 5
    • 1
    Middle Region
    Reactivity
    • 32
    • 19
    • 2
    Mouse
    Host
    • 45
    • 2
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAD1 antibody is un-conjugated
    Application
    • 23
    • 19
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    FPFNSFLSGF ISCVGSFILA VCLRIQINPQ NKADFQGISP ERAFADFLFA
    Characteristics
    This is a rabbit polyclonal antibody against DAD1. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the Middle region of Mouse DAD1
    Top Product
    Discover our top product DAD1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DAD1 (Defender Against Cell Death 1 (DAD1))
    Alternative Name
    DAD1 (DAD1 Products)
    Synonyms
    NV18456 antibody, dad1 antibody, DAD1 antibody, ost2 antibody, DAD-1 antibody, si:ch211-9d9.5 antibody, OST2 antibody, AI323713 antibody, DEFENDER AGAINST APOPTOTIC DEATH 1 antibody, F3C3.14 antibody, F3C3_14 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, defender against cell death 1 antibody, hypothetical protein antibody, defender against cell death 1 S homeolog antibody, Defender against death (DAD family) protein antibody, false DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1 antibody, LOC100115214 antibody, DAD1 antibody, dad1 antibody, CC1G_00458 antibody, CpipJ_CPIJ003512 antibody, PGTG_09898 antibody, Dad1 antibody, dad1.S antibody, ATDAD1 antibody, fdad1 antibody, dad-1 antibody
    Background
    DAD1 is an essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis.

    Protein Size: 113
    Gene ID
    13135
    NCBI Accession
    NP_034145
    UniProt
    P61804
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