DEDD antibody (Middle Region)

Catalog No. ABIN5515285

Product Details anti-DEDD Antibody

Target: DEDD (Death Effector Domain Containing (DEDD))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEDD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PTSGPQMCSK RPARGRATLG SQRKRRKSVT PDPKEKQTCD IRLRVRAEYC

Characteristics: This is a rabbit polyclonal antibody against DEDD. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human DEDD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Alternative Name: DEDD (DEDD Products)

Synonyms: CASP8IP1 antibody, DEDD1 antibody, DEFT antibody, FLDED1 antibody, Dedpro1 antibody, KE05 antibody, Deft antibody, death effector domain containing antibody, death effector domain-containing antibody, DEDD antibody, Dedd antibody

Background: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Alias Symbols: DEDD, DEDPRO1, DEFT, KE05,

Protein Interaction Partner: APLP2, SMAD3, BATF2, SHMT1, APP, UBC, HOXD4, USP22, DEDD2, GTF3C1, CFLAR, FADD, CASP8, CASP10, CASP3, KRT18, KRT8, GTF3C3, DEDD, CCDC59, RANBP3, KHK,

Protein Size: 318

Gene ID: 9191

NCBI Accession: NP_127491

UniProt: O75618