GSDMD antibody (Middle Region)

Catalog No. ABIN5515621

Product Details anti-GSDMD Antibody

Target: GSDMD (Gasdermin D (GSDMD))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSDMD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VTIPSGSTLA FRVAQLVIDS DLDVLLFPDK KQRTFQPPAT GHKRSTSEGA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GSDMD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Alternative Name: GSDMD (GSDMD Products)

Synonyms: GSDMDC1 antibody, GSDMD antibody, DF5L antibody, DFNA5L antibody, 1810036L03Rik antibody, AW558049 antibody, Dfna5l antibody, Gsdmdc1 antibody, M2-4 antibody, gasdermin D antibody, GSDMD antibody, Gsdmd antibody

Background: Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Alias Symbols: DF5L, DFNA5L, FKSG10, GSDMDC1

Protein Size: 484

Gene ID: 79792

NCBI Accession: NM_001166237, NP_001159709

UniProt: P57764

Pathways: Inflammasome