DUSP2 antibody (C-Term)

Catalog No. ABIN5515662

Product Details anti-DUSP2 Antibody

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SATICLAYLM QSRRVRLDEA FDFVKQRRGV ISPNFSFMGQ LLQFETQVLC

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DUSP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2 (DUSP2 Products)

Synonyms: zgc:91929 antibody, wu:fj40g04 antibody, PAC-1 antibody, PAC1 antibody, dual specificity phosphatase 2 antibody, dusp2 antibody, DUSP2 antibody, Dusp2 antibody

Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Alias Symbols: PAC1, PAC-1

Protein Size: 314

Gene ID: 1844

NCBI Accession: NM_004418, NP_004409

UniProt: Q05923