SREBF chaperone antibody (C-Term)

Catalog No. ABIN5515742

Product Details anti-SREBF chaperone Antibody

Target: SREBF chaperone (SCAP)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GPPPPSLFGD QPDLTCLIDT NFSAQPRSSQ PTQPEPRHRA VCGRSRDSPG

Characteristics: This is a rabbit polyclonal antibody against SCAP. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCAP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP (SCAP Products)

Synonyms: 9530044G19 antibody, mKIAA0199 antibody, SREBF chaperone antibody, SREBF chaperone S homeolog antibody, SCAP antibody, Scap antibody, scap.S antibody

Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

Alias Symbols: SCAP, KIAA0199, PSEC0227,

Protein Interaction Partner: ERLIN2, INSIG1, UBC, INSIG2, SREBF2, SREBF1, RNF139, SEC24B, SCAP, PGRMC1,

Protein Size: 1279

Gene ID: 22937

NCBI Accession: XP_006713097

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome