CYP2C8 antibody (C-Term)

Catalog No. ABIN5515918

Product Details anti-CYP2C8 Antibody

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Horse, Pig, Rabbit, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2C8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NPNIFDPGHF LDKNGNFKKS DYFMPFSAGK RICAGEGLAR MELFLFLTTI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CP2C8. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-CYP2C8 antibody is: synthetic peptide directed towards the C-terminal region of Human CP2C8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP2C8

Target: CYP2C8 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Alternative Name: CYP2C8 (CYP2C8 Products)

Synonyms: CPC8 antibody, CYPIIC8 antibody, MP-12/MP-20 antibody, CYP2C74 antibody, cpc8 antibody, cyp2c8 antibody, cypiic8 antibody, mp-12/mp-20 antibody, cytochrome P450 family 2 subfamily C member 8 antibody, Cytochrome P450 2C8 antibody, cytochrome P450, family 2, subfamily C, polypeptide 8 antibody, cytochrome P450 family 2 subfamily C member 8 S homeolog antibody, CYP2C8 antibody, CTN_0597 antibody, cyp2c8.1.S antibody, cyp2c8.1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene.

Alias Symbols: CPC8, CYPIIC8, MP-12/MP-20,

Protein Interaction Partner: PGRMC1, RNF32, EXOC6, ECSIT, MAST1, LONP1, PSEN1, IFIT3, DNAJB1, BLMH, APOE, A2M,

Protein Size: 388

Gene ID: 1558