DOC2B antibody (Middle Region)

Catalog No. ABIN5515999

Product Details anti-DOC2B Antibody

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTYLRPDVDK KSKHKTAVKK KTLNPEFNEE FCYEIKHGDL AKKSLEVTVW

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DOC2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOC2B

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Alternative Name: DOC2B (DOC2B Products)

Synonyms: DOC2BL antibody, multiple C2 and transmembrane domain-containing protein 1-like antibody, double C2 domain beta antibody, double C2-like domains, beta antibody, double C2, beta antibody, LOC100369196 antibody, DOC2B antibody, doc2b antibody, Doc2b antibody

Background: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells.

Alias Symbols: DOC2BL

Protein Size: 412

Gene ID: 8447

NCBI Accession: NM_003585, NP_003576

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion