GCAT antibody (Middle Region)

Catalog No. ABIN5516028

Product Details anti-GCAT Antibody

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCAT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TGPGPLVSLL RQRARPYLFS NSLPPAVVGC ASKALDLLMG SNTIVQSMAA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GCAT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GCAT

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Alternative Name: GCAT (GCAT Products)

Synonyms: kbl antibody, ECK3607 antibody, JW3592 antibody, KBL antibody, AI526977 antibody, Kbl antibody, glycine C-acetyltransferase S homeolog antibody, glycine C-acetyltransferase antibody, 2-amino-3-ketobutyrate CoA ligase antibody, Glycine C-acetyltransferase antibody, glycine c-acetyltransferase antibody, glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase) antibody, gcat.S antibody, gcat antibody, kbl antibody, Cagg_0385 antibody, Athe_2207 antibody, ABOO_RS03655 antibody, Mrub_1767 antibody, Mesil_2957 antibody, COB47_1985 antibody, Lbys_3455 antibody, Ftrac_1580 antibody, Pedsa_0139 antibody, GCAT antibody, Gcat antibody

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

Alias Symbols: KBL

Protein Size: 167

Gene ID: 23464

NCBI Accession: NM_001171690, NP_001165161

UniProt: O75600