SNAPIN antibody (Middle Region)

Catalog No. ABIN5516173

Product Details anti-SNAPIN Antibody

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAPIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LDPYVKKLLN ARRRVVLVNN ILQNAQERLR RLNHSVAKET ARRRAMLDSG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNAPIN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SNAPIN

Target: SNAPIN (SNAP-Associated Protein (SNAPIN))

Alternative Name: SNAPIN (SNAPIN Products)

Synonyms: SNAPAP antibody, si:dkey-222b8.2 antibody, SNAPIN antibody, BLOC1S7 antibody, BLOS7 antibody, 25kDa antibody, AA407989 antibody, AV026596 antibody, Bloc1s7 antibody, Snap25bp antibody, Snapap antibody, SNAP associated protein antibody, SNAP-associated protein L homeolog antibody, SNAP-associated protein antibody, SNAPIN antibody, snapin.L antibody, snapin antibody, Snapin antibody

Background: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Alias Symbols: BLOS7, SNAPAP, BLOC1S7,

Protein Size: 136

Gene ID: 23557

NCBI Accession: NM_012437, NP_036569

UniProt: O95295

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis