VPS33B antibody (Middle Region)

Catalog No. ABIN5516200

Product Details anti-VPS33B Antibody

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS33B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLSTLYGPFP NCYGIGRCAK MAYELWRNLE EEEDGETKGR RPEIGHIFLL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VPS33B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Alternative Name: VPS33B (VPS33B Products)

Synonyms: CG5127 antibody, Dmel\\CG5127 antibody, VPS33b antibody, Vps 33B antibody, dVps33B antibody, VPS33B antibody, GB11157 antibody, zgc:110803 antibody, Vacuolar protein sorting 33B antibody, VPS33B, late endosome and lysosome associated antibody, vacuolar protein sorting-associated protein 33B antibody, vacuolar protein sorting 33B antibody, Vps33B antibody, VPS33B antibody, LOC551135 antibody, Vps33b antibody, vps33b antibody

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.

Protein Size: 617

Gene ID: 26276

NCBI Accession: NM_001289148, NP_061138

UniProt: Q9H267