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ASCL1 antibody (N-Term)
ASCL1
Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog, Rabbit
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ASCL1 Antibody
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Target
See all ASCL1 Antibodies
ASCL1
(Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
Binding Specificity
All epitopes for ASCL1 antibodies
N-Term
Reactivity
All reactivities for ASCL1 antibodies
Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog, Rabbit
Host
All hosts for ASCL1 antibodies
Rabbit
Clonality
All clonalities for ASCL1 antibodies
Polyclonal
Conjugate
All conjugates for ASCL1 antibodies
This ASCL1 antibody is un-conjugated
Application
All applications for ASCL1 antibodies
Western Blotting (WB)
Sequence
QAPQLRPAAD GQPSGGGHKS APKQVKRQRS SSPELMRCKR RLNFSGFGYS
Predicted Reactivity
Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 85%
Characteristics
This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human ASCL1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for ASCL1
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Target
ASCL1
(Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
Alternative Name
ASCL1 (ASCL1 Products )
Synonyms
ASH1 antibody, HASH1 antibody, MASH1 antibody, bHLHa46 antibody, AI225900 antibody, Mash1 antibody, ASCL1 antibody, Zash-1a antibody, ash antibody, asha antibody, id:ibd5085 antibody, im:7138587 antibody, si:dkey-264k15.2 antibody, zash1a antibody, zasha antibody, Xash1 antibody, ascl1-A antibody, Zash-1b antibody, ashb antibody, zashb antibody, achaete-scute family bHLH transcription factor 1 antibody, achaete-scute family bHLH transcription factor 1a antibody, achaete-scute family bHLH transcription factor 1 L homeolog antibody, achaete-scute complex homolog 1 antibody, achaete-scute family bHLH transcription factor 1b antibody, ASCL1 antibody, Ascl1 antibody, ascl1a antibody, ascl1.L antibody, LOC100220505 antibody, ascl1b antibody
Background
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. Alias Symbols: ASCL1, ASH1, BHLHA46, HASH1, Protein Size: 236
Gene ID
429
NCBI Accession
NP_004307
UniProt
P50553
Pathways
Dopaminergic Neurogenesis
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