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ASCL1 antibody (N-Term)

ASCL1 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5516449
  • Target See all ASCL1 Antibodies
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Binding Specificity
    • 21
    • 15
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 85
    • 44
    • 27
    • 9
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Guinea Pig, Dog, Rabbit
    Host
    • 85
    • 5
    • 2
    Rabbit
    Clonality
    • 87
    • 5
    Polyclonal
    Conjugate
    • 40
    • 11
    • 9
    • 9
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASCL1 antibody is un-conjugated
    Application
    • 79
    • 60
    • 28
    • 13
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    QAPQLRPAAD GQPSGGGHKS APKQVKRQRS SSPELMRCKR RLNFSGFGYS
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot.
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ASCL1
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    Discover our top product ASCL1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))
    Alternative Name
    ASCL1 (ASCL1 Products)
    Synonyms
    ASH1 antibody, HASH1 antibody, MASH1 antibody, bHLHa46 antibody, AI225900 antibody, Mash1 antibody, ASCL1 antibody, Zash-1a antibody, ash antibody, asha antibody, id:ibd5085 antibody, im:7138587 antibody, si:dkey-264k15.2 antibody, zash1a antibody, zasha antibody, Xash1 antibody, ascl1-A antibody, Zash-1b antibody, ashb antibody, zashb antibody, achaete-scute family bHLH transcription factor 1 antibody, achaete-scute family bHLH transcription factor 1a antibody, achaete-scute family bHLH transcription factor 1 L homeolog antibody, achaete-scute complex homolog 1 antibody, achaete-scute family bHLH transcription factor 1b antibody, ASCL1 antibody, Ascl1 antibody, ascl1a antibody, ascl1.L antibody, LOC100220505 antibody, ascl1b antibody
    Background
    This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

    Alias Symbols: ASCL1, ASH1, BHLHA46, HASH1,

    Protein Size: 236
    Gene ID
    429
    NCBI Accession
    NP_004307
    UniProt
    P50553
    Pathways
    Dopaminergic Neurogenesis
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