FBXO22 antibody (Middle Region)

Catalog No. ABIN5516515

Product Details anti-FBXO22 Antibody

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO22 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VVTPMGSGSN RPQEIEIGES GFALLFPQIE GIKIQPFHFI KDPKNLTLER

Characteristics: This is a rabbit polyclonal antibody against FBX22. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human FBX22

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Alternative Name: FBX22 (FBXO22 Products)

Synonyms: FBXO22 antibody, DKFZp469L0535 antibody, fbxo22 antibody, MGC146708 antibody, si:busm1-132m23.3 antibody, FBX22 antibody, FISTC1 antibody, 0610033L19Rik antibody, 1600016C16Rik antibody, F-box protein 22 antibody, FBXO22 antibody, fbxo22 antibody, Fbxo22 antibody

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Alias Symbols: FBXO22, FBX22,

Protein Interaction Partner: Srr, UBC, CUL1, SKP1, NEDD8, COPS5, COPS6, RBX1,

Protein Size: 403

Gene ID: 26263

NCBI Accession: NP_671717

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development