AP4E1 antibody (Middle Region)

Catalog No. ABIN5516602

Product Details anti-AP4E1 Antibody

Target: AP4E1 (Adaptor-Related Protein Complex 4, epsilon 1 Subunit (AP4E1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP4E1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CSSFSSLSNV AYEDDYYSNT LHDTGDKELK KFSLTSELLD SESLTELPLV

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AP4E1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AP4E1

Target: AP4E1 (Adaptor-Related Protein Complex 4, epsilon 1 Subunit (AP4E1))

Alternative Name: AP4E1 (AP4E1 Products)

Synonyms: CPSQ4 antibody, SPG51 antibody, RGD1562199 antibody, 2310033A20Rik antibody, 9930028M04Rik antibody, AV087807 antibody, adaptor related protein complex 4 epsilon 1 subunit antibody, adaptor-related protein complex 4, epsilon 1 subunit antibody, adaptor-related protein complex AP-4, epsilon 1 antibody, AP4E1 antibody, Ap4e1 antibody

Background: This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: CPSQ4, SPG51

Protein Size: 1137

Gene ID: 23431

NCBI Accession: NM_001252127, NP_001239056

UniProt: Q9UPM8