EPH Receptor A8 antibody (Middle Region)

Catalog No. ABIN5516708

Product Details anti-EPH Receptor A8 Antibody

Target: EPH Receptor A8 (EPHA8)

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YKKCPAMVRN LAAFSEAVTG ADSSSLVEVR GQCVRHSEER DTPKMYCSAE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPHA8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPH Receptor A8

Target: EPH Receptor A8 (EPHA8)

Alternative Name: EPHA8 (EPHA8 Products)

Synonyms: TK antibody, tke17-a antibody, si:ch211-122l14.1 antibody, EPHA8 antibody, EEK antibody, EK3 antibody, HEK3 antibody, AW047546 antibody, Eek antibody, Hek3 antibody, mKIAA1459 antibody, EPH receptor A8 L homeolog antibody, EPH receptor A8 antibody, eph receptor A8 antibody, Eph receptor A8 antibody, epha8.L antibody, EPHA8 antibody, epha8 antibody, Epha8 antibody

Background: This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.

Alias Symbols: EEK, EK3, HEK3

Protein Interaction Partner: DARS2, G3BP1, PSMC5, AK4, ZNF746, ANKS1A, UBC, CBL, EFNA5, EFNA4, PIK3CG, EFNA1, EPHA8, FYN,

Protein Size: 495

Gene ID: 2046

NCBI Accession: NM_001006943, NP_001006944

Pathways: RTK Signaling