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KALRN antibody (Middle Region)
KALRN
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KALRN Antibody
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Target
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KALRN
(Kalirin, RhoGEF Kinase (KALRN))
Binding Specificity
All epitopes for KALRN antibodies
Middle Region
Reactivity
All reactivities for KALRN antibodies
Human
Host
All hosts for KALRN antibodies
Rabbit
Clonality
All clonalities for KALRN antibodies
Polyclonal
Conjugate
All conjugates for KALRN antibodies
This KALRN antibody is un-conjugated
Application
All applications for KALRN antibodies
Western Blotting (WB)
Sequence
QGDSADEKSK KGWGEDEPDE ESHTPLPPPM KIFDNDPTQD EMSSLLAARQ
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human KALRN
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for KALRN
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Target
KALRN
(Kalirin, RhoGEF Kinase (KALRN))
Alternative Name
KALRN (KALRN Products )
Synonyms
ARHGEF24 antibody, CHD5 antibody, CHDS5 antibody, DUET antibody, DUO antibody, HAPIP antibody, TRAD antibody, KALRN antibody, 2210407G14Rik antibody, AV235988 antibody, E530005C20Rik antibody, Gm539 antibody, Hapip antibody, Duo antibody, Kalirin antibody, kalirin RhoGEF kinase antibody, kalirin, RhoGEF kinase antibody, kalirin antibody, kalirin RhoGEF kinase L homeolog antibody, putative kalirin antibody, KALRN antibody, LOC460643 antibody, Kalrn antibody, kalrn antibody, kalrn.L antibody, LOC100473997 antibody, Smp_162970 antibody
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. Alias Symbols: DUO, CHD5, DUET, TRAD, CHDS5, HAPIP, ARHGEF24 Protein Size: 738
Gene ID
8997
NCBI Accession
NM_001024660 , NP_001019831
Pathways
Neurotrophin Signaling Pathway
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