HNRPLL antibody (Middle Region)

Catalog No. ABIN5516787

Product Details anti-HNRPLL Antibody

Target: HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRPLL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AQKAKAALNG ADIYAGCCTL KIEYARPTRL NVIRNDNDSW DYTKPYLGRR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNRPLL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRPLL

Target: HNRPLL (Heterogeneous Nuclear Ribonucleoprotein L-Like (HNRPLL))

Alternative Name: HNRPLL (HNRPLL Products)

Synonyms: HNRPLL antibody, SRRF antibody, 2510028H02Rik antibody, 2810036L13Rik antibody, AI256697 antibody, AI852082 antibody, Hnrpll antibody, RGD1305861 antibody, srrf antibody, heterogeneous nuclear ribonucleoprotein L like antibody, heterogeneous nuclear ribonucleoprotein L-like antibody, Heterogeneous nuclear ribonucleoprotein L-like antibody, heterogeneous nuclear ribonucleoprotein L antibody, HNRNPLL antibody, Hnrnpll antibody, HNRPLL antibody, hnrnpll antibody, LOC100160547 antibody, hnrll antibody, LOC100542006 antibody, LOC100638467 antibody, LOC100647365 antibody, HNRNPL antibody

Background: HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC, MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008]

Alias Symbols: SRRF, HNRPLL

Protein Size: 542

Gene ID: 92906

NCBI Accession: NM_001142650, NP_001136122

UniProt: Q8WVV9