VPREB3 antibody (Middle Region)

Catalog No. ABIN5516860

Product Details anti-VPREB3 Antibody

Target: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPREB3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TIRDYGVSWY QQRAGSAPRY LLYYRSEEDH HRPADIPDRF SAAKDEAHNA

Characteristics: This is a rabbit polyclonal antibody against VPREB3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human VPREB3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VPREB3

Target: VPREB3 (Pre-B Lymphocyte 3 (VPREB3))

Alternative Name: VPREB3 (VPREB3 Products)

Synonyms: 8HS-20 antibody, Vpreb-3 antibody, AI528709 antibody, VPREB3 antibody, 8HS20 antibody, N27C7-2 antibody, pre-B lymphocyte gene 3 antibody, V-set pre-B cell surrogate light chain 3 antibody, pre-B lymphocyte 3 antibody, Ig lambda-6 chain C region antibody, Vpreb3 antibody, VPREB3 antibody, LOC698694 antibody

Background: The protein encoded by this gene is the human homolog of the mouse VpreB3 (8HS20) protein, and is specifically expressed in cell lines representative of all stages of B-cell differentiation. It is also related to VPREB1 and other members of the immunoglobulin supergene family. This protein associates with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. The precise function of the protein is not known, but it may contribute to mu chain transport in pre-B cells.

Alias Symbols: VPREB3, UNQ355/PRO619,

Protein Interaction Partner: VPREB1, IGHM,

Protein Size: 123

Gene ID: 29802

NCBI Accession: NP_037510

UniProt: Q9UKI3

Pathways: Production of Molecular Mediator of Immune Response